You want fast, safe access to Aciclovir without chasing appointments. You also don’t want to fall for sketchy sites shipping mystery pills. Here’s the short promise: you can order Aciclovir legally online in the UK, same-day or next-day in many cases, as long as you use a UK-registered online pharmacy and complete a quick health check. I’ll show you what you can buy, what it should cost, how to avoid fakes, and the exact steps to place an order today.
What you can buy online (and who it’s for)
Aciclovir (also spelled acyclovir) is an antiviral used for cold sores, genital herpes, and shingles. In the UK, the rules depend on the form:
- 5% cream (e.g., Zovirax): pharmacy medicine for cold sores. You can usually buy it without a prescription, but a pharmacist may ask questions.
- Tablets (200 mg, 400 mg, 800 mg): prescription-only. Online pharmacies can prescribe after a short questionnaire reviewed by a UK-registered prescriber.
- Suspension (liquid) and IV: prescription-only and not typically supplied via online retail pharmacies to the public.
Typical uses:
- Cold sores: 5% cream at the tingle stage; tablets if outbreaks are frequent, severe, or you’re at higher risk (your clinician decides).
- Genital herpes: tablets for first episodes and recurrences; sometimes a longer daily “suppression” plan if outbreaks are frequent.
- Shingles: tablets (usually 800 mg, five times daily) within 72 hours of the rash starting, if appropriate for you.
What to expect from a legit UK online service in 2025:
- A short clinical assessment (about 3-5 minutes). They’ll ask about symptoms, timing, kidney health, other meds, pregnancy/breastfeeding.
- Identity and age checks when needed.
- Clear product options, dosing set by the prescriber, and a price that includes the private prescription and dispensing fee. Delivery is extra but usually cheap.
“Aciclovir is an antiviral medicine used to treat infections caused by the herpes virus, such as cold sores, genital herpes and shingles.” - NHS Medicines Information
Note for first-time genital herpes: many services won’t supply without ruling out other causes or complications. They may ask you to attend a sexual health clinic if it’s the first episode or if you have severe symptoms.
Prices, prescriptions, and delivery in the UK
Private online pricing varies by pharmacy, dose, and pack size. In 2025, this is the ballpark you should see for common options (medicine price often includes the consultation and private prescription):
Form | Typical UK Use | Common Regimen | Typical Online Price (2025) | Rx Status | Notes |
---|---|---|---|---|---|
Aciclovir 5% cream (2g) | Cold sores (lip) | Apply 5x daily for 5 days | £4-£9 | Pharmacy medicine (no prescription) | Buy online or in-store; pharmacist may ask questions |
Aciclovir tablets 200 mg | Genital herpes (recurrence) | 200 mg 5x daily for 5 days (prescriber may vary) | £8-£16 per course | Prescription-only | Online consultation required |
Aciclovir tablets 400 mg | Genital herpes (recurrence or suppression) | 400 mg 3x daily for 5 days, or 400 mg 2x daily (suppression) | £9-£22 per course; £20-£40 per month (suppression) | Prescription-only | Suppression plans often sold in 1-3 month supplies |
Aciclovir tablets 800 mg | Shingles | 800 mg 5x daily for 7 days (timing critical) | £12-£28 per course | Prescription-only | Usually supplied faster shipping; some services refer urgently to GP |
Valaciclovir tablets (alt.) | Genital herpes & shingles | Less frequent dosing vs aciclovir | £15-£45 per course | Prescription-only | Often chosen for convenience; higher price |
Delivery and timing:
- Standard tracked: 2-3 working days, often £2.99-£4.99.
- Next-day: cut-off times apply (often 3-5 pm on weekdays), £5.99-£8.99.
- Same-day courier: limited to major cities; prices vary and can be £8-£15+.
Payment and terms you should see in 2025:
- Clear breakdown: consultation/prescription included, VAT where applicable, delivery shown upfront.
- Receipts with the prescriber’s name and registration number.
- Returns: medicines cannot be resold, so refunds are limited to dispatch errors or damaged goods.
Important: NHS prescriptions are different. If your GP issues an NHS script, the usual NHS charge applies in England (free in Scotland, Wales, Northern Ireland), and the pharmacy fulfills via the Electronic Prescription Service. Private online services are a separate route and not covered by the NHS.
Safe-buying checklist and how to spot fakes
The UK tightened online medicine rules. Any site selling medicines to UK patients must be properly registered and follow strict standards. Use this quick checklist before you buy aciclovir online:
- Check the pharmacy’s GPhC registration: the site should display the pharmacy’s name and General Pharmaceutical Council number; you can verify it on the GPhC register (searchable by name/number).
- Look for the UK distance selling logo that clicks through to the MHRA register entry for that specific website domain.
- There’s always a health questionnaire for tablets. If a site sells aciclovir tablets without any questions or prescription, walk away.
- Pricing makes sense. If it’s unbelievably cheap, it’s likely not legitimate or is shipping from overseas without UK oversight.
- Clear contact details and a superintendent pharmacist named on the site.
- UK-licensed medicine images and patient information leaflets (PILs) that match UK packs.
Red flags:
- No UK address or registration info; vague “about us.”
- Claims to ship from “EU/USA/Worldwide warehouses” for a UK prescription drug without a UK prescriber.
- Pushy “limited time” urgency on prescription medicines.
- No returns policy, no privacy policy, or broken links.
When you might be redirected to in-person care:
- First-ever episode of genital sores, severe pain, fever, or ulcers that don’t look typical.
- Pregnancy or breastfeeding-treatment can be safe, but needs proper assessment.
- Kidney disease or medicines that affect kidneys (e.g., certain diuretics, ciclosporin)-dosing may change.
- Shingles close to the eye or on the face-urgent same-day medical advice is needed.
Why all the checks? UK regulators (MHRA and GPhC) require safe prescribing and supply. It protects you from counterfeit products and dosing errors.

Aciclovir vs valaciclovir vs OTC creams: what to choose
Aciclovir and valaciclovir both tackle the same viruses; valaciclovir converts to aciclovir in the body and often needs fewer daily doses. Here’s how to think about the options:
- Cold sores on lips: start with 5% cream at the tingle phase. It’s cheap and accessible. If outbreaks are frequent or severe, speak to a prescriber about tablets.
- Genital herpes recurrence: aciclovir tablets work well and are affordable; valaciclovir is popular if you want fewer doses per day.
- Suppression (frequent outbreaks): either drug can be used long-term; valaciclovir often wins on convenience, aciclovir on cost.
- Shingles: timing is crucial-whichever drug is prescribed, starting within 72 hours is the big win.
Simple decision guide:
- If it’s a cold sore you’ve had many times and you caught the tingle early: order 5% cream online or pick it up at a local pharmacy.
- If you’re having a typical recurrence of genital herpes and you’ve been treated before: an online consultation for aciclovir tablets is reasonable.
- If this is your first genital outbreak, or you feel unwell, or you’re pregnant: book GP/sexual health clinic-don’t rely on a click-and-ship.
- If you suspect shingles: act fast. Some online services will assess and prescribe the same day; if your eye is involved, seek urgent same-day care.
Pros and cons at a glance:
Option | Best for | Pros | Cons |
---|---|---|---|
Aciclovir cream | Cold sores, early stage | OTC access, low cost | Needs early use; limited effect once blistered |
Aciclovir tablets | Genital herpes, shingles | Effective, affordable | More daily doses; needs prescription |
Valaciclovir tablets | Convenience-focused users | Less frequent dosing | Higher price |
Side effects and cautions (general):
- Common: nausea, headache, dizziness; usually mild and short-lived.
- Rare but important: kidney issues (more likely if dehydrated or with existing kidney disease). Drink water and follow dosing.
- Drug interactions: check with the prescriber if you take medicines that can affect kidneys.
Evidence note: UK guidance (NICE, NHS) prioritises early antiviral treatment for shingles and supportive, patient-led plans for recurrent herpes. Dose and duration are set by your prescriber based on your history and renal function.
How to order step-by-step (UK-registered online pharmacy)
Here’s the smooth, safe path most legit UK services follow:
- Find a registered site.
- Check the GPhC register entry and the MHRA distance selling logo that links to the site’s domain record.
- Choose your treatment pathway.
- Cold sores only? Pick 5% aciclovir cream and add to basket.
- Tablets? Start the online consultation for aciclovir or valaciclovir.
- Complete the health questionnaire.
- Be honest about symptoms, timing, past diagnoses, kidney history, pregnancy/breastfeeding, and current meds.
- Clinical review.
- A UK prescriber reviews your answers. They may message you for clarification or recommend a different option.
- Pay and choose delivery.
- Review the total including prescription and shipping. Pick next-day if timing matters (e.g., shingles).
- Receive discreet, trackable delivery.
- Package includes the pharmacy label, PIL, and contact route for questions.
- Use as directed.
- Follow the label. If symptoms worsen, or eye/face involvement appears with shingles, seek urgent care.
Pro tips:
- Order early in the day if you need next-day delivery; most pharmacies have afternoon cut-offs.
- Keep a small reserve if you’re on suppression (with your prescriber’s approval) to avoid gaps during holidays.
- Photograph your rash only if the service asks-don’t delay treatment to chase the perfect photo.
Common pitfalls (and fixes):
- Waiting too long for shingles: antiviral benefit drops after 72 hours. If you’re close to the window, choose the fastest delivery or seek in-person care.
- Misreading doses: aciclovir can be several times per day-set phone reminders.
- Skipping hydration: drink water to reduce kidney strain, especially with higher doses.
Ethical CTA: use a UK-registered online pharmacy or speak to your GP/sexual health clinic. Avoid overseas sites that bypass UK checks. Your safety and the quality of the medicine matter more than a small price difference.
FAQs and next steps
Is aciclovir safe in pregnancy?
Aciclovir is often considered when needed in pregnancy, but you must be assessed first. Online services may signpost you to your GP or maternity team for tailored advice.
What if I keep getting outbreaks?
Ask about suppression therapy (daily tablets for several months). Many UK online services can prescribe this if it’s right for you, with periodic reviews.
Can I get NHS aciclovir through an online pharmacy?
Yes, if your GP sends an NHS electronic prescription to a pharmacy that offers delivery. That’s different from private online prescribers and may be cheaper depending on exemptions and location.
Do I need tests first?
For typical cold sores, no. For genital herpes, diagnosis from a clinician helps guide treatment, especially for the first episode. Persistent or unusual sores should be examined.
How do I store it?
Room temperature, away from direct heat and sunlight. Check the expiry date. Don’t share your medicine.
What if I have kidney disease?
You need tailored dosing. Flag this in the questionnaire and speak to the prescriber. Do not self-dose.
Next steps by scenario:
- Cold sore starting today: order 5% cream now; consider next-day if you’re late in the 72-hour window; apply five times daily.
- Genital herpes recurrence and you’ve used aciclovir before: complete an online consultation for a 5-day course; ask about valaciclovir if dosing frequency is hard for you.
- First-ever genital outbreak: book a sexual health clinic or GP. If an online service is available, expect careful triage and possible referral.
- Shingles within 72 hours: seek same-day assessment if possible; if using an online service, choose express delivery and watch for eye symptoms (urgent care if involved).
Credibility notes:
- NHS Medicines Information describes aciclovir’s uses and common dosing for cold sores, genital herpes, and shingles.
- MHRA: UK online medicine sellers must be registered and display a distance selling logo that links to the official register.
- GPhC: check the pharmacy’s registration and superintendent pharmacist on the public register.
- NICE and UK clinical guidance prioritise early treatment for shingles and individualised plans for recurrent herpes.
If you remember one rule, make it this: buy from a UK-registered pharmacy that asks the right questions. That’s how you get genuine aciclovir, the right dose, and speedy, safe relief.