TREATMENTS FOR THE CRAMPS: CURRENT THINKING-NEW DRUGS

Doctors now are turning their attention to hormones, and they've looked at two in particular that they think might cause the cramps.
A treatment for the cramps-New drugs-It is known that some of the hormones called prostaglandins can make your womb contract. Women who suffer from the cramps know how painful those contractions can be. One way of cutting down the pain might be to reduce the amount of certain prostaglandins which your body produces, so contractions aren't so strong. Doctors in London and Oxford have been carrying out clinical trials with two drugs called mefenamic and flufenamic acid that cut back the amount of prostaglandin you produce. The women who took part in the trials all suffered from the cramps and vomiting and diarrhoea, and the doctors were very encouraged by the results. Of the thirty patients at Oxford and the
forty-four in London, eighty-two per cent found the drugs relieved the pain, sixty-six per cent had less vomiting, and fifty-two per cent less diarrhoea. Unfortunately, like most drugs, these two had some unpleasant side-effects. Thirteen women dropped out of the trials altogether, so the treatment wasn't for them. Some patients found they felt dizzy and sick while they were taking the pills. So, as you can see, there are problems with the treatment that remain to be solved.
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TAKING ESTROGEN

With the onset of menopause, many women suffer from hot flashes and night sweats. Arlene March, 56, a Los Angeles psychotherapist, says she started getting hot flashes 5 years ago. “I’d be working,” she recalls, “and suddenly feel intense heat all over my body. I’d break out in a sweat. I’d have to stop work. Then Dr. Mishell prescribed estrogen pills, and I’ve not had a day of discomfort.”
Some women experience a drying and thinning of vaginal tissues in the absence of estrogen, making sex painful. They also might suffer urinary tract infections and incontinence. Estrogen therapy often helps.
Among the physicians consulted, the most cautious was Dr. Morris Notelovitz, founder of the nation’s first Menopause Center, at the University of Florida, and head of the Women’s Medical and Diagnostic Center in Gainesville, Florida. He says each symptom needs a different treatment and advises that genital tract problems be given estrogen treatment for a couple of years at most. He also urges special measurements of the bones before prescribing estrogen therapy for osteoporosis.
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WOMEN’S HEALTH

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